# nitrogen gas death

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death » Ferroptosis is a form of regulated necrosis associated with the iron-dependent accumulation of lipid hydroperoxides that may play a key role in the pathogenesis of degenerative diseases in which lipid peroxidation has been implicated. High-throughput screening efforts have identified ferrostatin-1 (Fer-1) and liproxstatin-1 (Lip-1) as potent inhibitors of ferroptosis − an activity that has been ascribed to their ability to slow the accumulation of lipid hydroperoxides. Herein we demonstrate that this activity likely derives from their reactivity as radical-trapping antioxidants (RTAs) rather than their potency as inhibitors of lipoxygenases. Although inhibited autoxidations of styrene revealed that Fer-1 and Lip-1 react roughly 10-fold more slowly with peroxyl radicals than reactions of α-tocopherol (α-TOH), they were significantly more reactive than α-TOH in phosphatidylcholine lipid bilayers − consistent with the greater potency of Fer-1 and Lip-1 relative to α-TOH as inhibitors of ferroptosis. None Pubs.acs.org

Stupid Question: Do pro XC racers fill their tires with… » Jan 25, 2021… Well, we're talking 10s of grams for the gas weight inside the tires, so it isn't worth the fuss for weight savings. Mtbr.com

Chokes » Chokes is a colloquial term used by divers that denotes a potentially fatal pulmonary form of decompression sickness (DCS). The condition may arise when deep divers ascend to the surface too quickly or fail to follow proper decompression procedures. Notable symptoms include shortness of breath, chest pain, and coughing. The symptoms of pulmonary DCS can arise from more common conditions like asthma and acute coronary syndrome (ACS). Therefore, clinicians can easily miss this rare diagnosis and fail or delay administering the appropriate treatment. Ncbi.nlm.nih.gov